You receive the error “One or more McAfee Point Product(s) cannot be updated by this package. Please run an appropriate package to update the Point Product(s)” when trying to manually update McAfee Virus Scan Enterprise 8.0
You cannot update McAfee VirusScan Enterprise 8.0.0 after March 31st 2010 as they use V1 DAT files which are now obsolete. The newer V2 DAT files are not compatible with v 8.0.0 and earlier, meaning that you cannot apply any further updates. This will leave the client PC vulnerable to attack from newer viruses as a result.
Additionally and conveniently for McAfee, VirusScan Enterprise 8.0.0 also became end of life after March 31st 2010.
I would recommend that you replace this version with a supported later version or an alternative supported AV product.
Official details here: